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Reference
Reference

Rig setup

Pick what you're plugging into. You get the cabling, the cab block state, and the thing that goes wrong.

One rule covers most of it

Cab block ON for anything full-range: headphones, FRFR speakers, front of house, your computer. Cab block OFF for anything that ends in a real guitar speaker. A cab block is a speaker simulation, so using one into a real cab gives you two speakers stacked, and leaving it off into a full-range system gives you a raw amp with no speaker at all.

Quad Cortex User Manual 4.0.0 · Quad Cortex Wiki: Using the Quad Cortex with a Real Amp
What are you plugging into?
Cab sim

Leave it on

You're feeding a full-range system, so the Nano has to supply the speaker.

Nothing to get wrong here.

The simplest way to use it, and where most people start on day one.

Hook it up
  1. GuitarINPUT 1

    Ordinary guitar cable

  2. HeadphonesHeadphone jack on the rear
Set it up
Cab block
On
Input level
0 dB
Check it once — play hard and watch the meter just touch the red.
VOLUME knob
Start low and bring it up
Once it works
  • The headphone output drives up to 300 ohms, which covers most headphones but not every high-impedance studio pair.

    Quad Cortex product page
The shortcut

When you need cab blocks off, use Global Bypass rather than editing presets. It switches off every cab, IR and capture block across all your presets at once, and switching it back restores them.

Quad Cortex Wiki: FAQ